Never been to Ohio myself but the east wing thing rings bells with me - I've noticed it's almost always one specific part of a building that feels wrong rather than the whole place. Had that at a Victorian workhouse near Kings Lynn a few years back, perfectly fine in most of it then you walk through one doorway and the temperature just drops and you feel like you shouldn't be there.
Did you get any recordings while you were in there? I do a lot of EVP work and places like old sanitariums are genuinely fascinating for it. Teh amount of residual energy in a building like that, decades of people in real distress, it has to go somewhere doesn't it.
What specifically felt off - was it more of an emotional thing, like dread or being watched, or were there actual physical things happening? Would love to hear more detail if you've got it.