Never been to that particular one but Denver has some serious residual energy in certain buildings, a lot of that city sits on very old ground with a complicated history.
Room 4 specifically though - that's interesting. Numbers do seem to matter with hauntings, certain rooms in hotels come up again and again in reports and its not random. I've seen the same thing with Warwick Castle over the years, always the same spots that generate activity regardless of who's staying there.
What exactly happened to you? Was it temperature, sounds, visual, or more of a feeling you couldn't shake? The "something is off" sensation is usually the most reliable indicator in my experience, your instincts are picking up on something before your conscious mind catches up. That's not nothing, that's data.
Would be curious if anyone else has stayed there recently and had similar.